|
KMID : 0363620100310040001
|
|
Journal of Korean Oriental Medicine
2010 Volume.31 No. 4 p.1 ~ p.8
|
|
|
Randomized Clinical Controlled Trials of a Herb Remedies in Korea - Systematic Review
|
|
Oh Rai-Young
Seol In-Chan
Son Chang-Gue
|
|
|
Abstract
|
|
|
Objective: The study aimed to review all randomized controlled clinical trials (RCTs) performed in Korea with herbal medicine, to produce further useful information for herbal-drug development.
Methods: All papers reporting RCT with herbal drugs were collected via public database of Korea Science and Technology Integration Services, and various Oriental medicine journals. Then, the clinical question, herbal medicine, result, RCT design, and its conductor were analyzed.
Results: A total of 20 RCTs were finally selected, and most of them were performed after 2003. The main subjects of RCT were related to heart and blood circulation, dermatitis, respiration disorder, Sasang constitution, or psychiatric disorders. Eight RCTs were done with a single herb while 12 RCTs were with multiple herbal formulae. In particular, three RCTs for atopic dermatitis with three formulae showed positive results. The quality of RCT was considered as better than average.
Conclusions: This study revealed the current status of RCT using herbal drugs. This result would provide helpful information for research and drug development using traditional herbal medicine.
|
|
|
KEYWORD
|
|
|
Clinical trial, clinical research, RCT, tang, traditional Korean medicine
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|